Massachusetts Institute of Technology
Sign in | Create Account

Neurobiology of Memory: How Do We Acquire, Consolidate and Recall Memory

06/12/2003 9:00 AM 3-170
Susumu Tonegawa, Director, Picower Institute for Learning and Memory; ; Picower Professor of Biology and Neuroscience, Departments of Biology and Brain and Cognitive Sciences

Description: In labs around the world, mice learn to navigate complex mazes, locate chocolaty rewards, and after an interval, run the mazes again with maximum efficiency, swiftly collecting all the sweets. But in Susumu Tonegawa's lab, the mutant mice he has created cannot perform these tasks. Tonegawa " knocks out" a gene that impairs a specific part of the mouse hippocampus, the area of the brain responsible for spatial memory, among other things. Mutant mice struggle to acquire and recall information about their surroundings. Tonegawa's work involves manipulating genes to explore memory and learning from the most basic biochemical and cellular levels, up to the most complex behaviors. One of Tonegawa's goals in designing defective mice is to simulate profound human disorders, like schizophrenia.

About the Speaker(s): Susumu Tonegawa has received the highest honors for his work, including the 1987 Nobel Prize in Physiology or Medicine, the Albert and Mary Lasker Award and the Bristol Myers Squibb Prize in Cancer Research. He was awarded his Ph.D. in Molecular Biology from the University of California at San Diego and trained at the Salk Institute as a postdoctoral student. In 1981, he was appointed Professor of Biology at MIT and a member of the Center for Cancer Research. He founded the Picower Center for Learning and Memory in 1994.

Host(s): School of Science, School of Science

Comments (0)

It looks like no one has posted a comment yet. You can be the first!

You need to log in, in order to post comments. If you don’t have an account yet, sign up now!

MIT World — special events and lectures

MIT World — special events and lectures

Category: Events | Updated over 2 years ago

Created
December 12, 2011 17:57
Category
Tags
License
All Rights Reserved (What is this?)
Additional Files


Viewed
1466 times

More from MIT World — special events and lectures

Reverberations: Mexico City's 1985 Earthquake and the Transformation of the Capital

Reverberations: Mexico City's 1985 ...

Added over 2 years ago | 01:12:00 | 2227 views

Energy and Emissions Logging in Road Vehicles

Energy and Emissions Logging in Roa...

Added over 2 years ago | 00:54:06 | 6743 views

Leadership in a Complex, Technology-Driven World

Leadership in a Complex, Technology...

Added over 2 years ago | 01:24:00 | 1561 views

Why So Slow? The Advancement of Women

Why So Slow? The Advancement of Women

Added over 2 years ago | 01:31:00 | 1566 views

Kofi Annan Keynote Address

Kofi Annan Keynote Address

Added over 2 years ago | 00:39:50 | 1551 views

What Does Re-Engineering Mean for Real Estate?

What Does Re-Engineering Mean for R...

Added over 2 years ago | 01:13:00 | 3447 views